Arsenal manager Arsene Wenger has made one change from the side who disappointing drew 3-3 with Anderlecht on Tuesday, bringing in Mathieu Flamini for Mikel Arteta, who has a hamstring injury.
Theo Walcott is on the bench for the Gunners as he continues his recovery from a knee ligament injury.
Per Mertesacker will be lead out Arsenal on his 100th Premier League appearance.
Lukasz Fabianski starts in goal for the Swans against his former team. Tom Carroll, on loan from Tottenham, is also named in the starting XI.
Arsenal: Szczesny, Chambers, Mertesacker, Monreal, Gibbs, Flamini, Oxlade-Chamberlain, Ramsey, Alexis, Cazorla, Welbeck.
Subs: Martinez, Bellerin, Rosicky, Wilshere, Podolski, Walcott, Sanogo
Swansea: Fabianski, Rangel, Bartley, Williams, Taylor, Ki, Carroll, Sigurdsson, Emnes, Montero, Bony
Subs: Tremmel, Tiendalli, Amat, Britton, Fulton, Barrow, Gomis.
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