Diabetes medication can cut risk of heart failure by more than a quarter, scientists find

Well-known diabetes drug can cut causes of death by heart failure, scientists find in large-scale study

Conor Riordan
Monday 02 September 2019 07:18 BST
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Dapagliflozin was also found to benefit patients without diabetes
Dapagliflozin was also found to benefit patients without diabetes

A common diabetes medication can be used to treat patients with heart failure, according to new research.

Scientists have found dapagliflozin – a drug that helps control blood sugar levels – can also reduce the risk of cardiovascular conditions worsening or causing death by more than 25 per cent.

The medicine also cut the chances of death from any cause by 17 per cent in patients with established heart failure and hospital admission with worsening heart failure by 30 per cent.

John McMurray, professor of cardiology at the University of Glasgow, said: “These are really once in a lifetime findings that show that a commonly prescribed drug for diabetes can effectively be used to treat people with heart failure.

“Probably the most important finding of all is that dapagliflozin was associated with benefit in patients without diabetes.

“With dapagliflozin, we did the three things you want to do for the patient in the ideal world – make them feel better, keep them out of hospital and keep them alive. That’s why we’re so delighted with the results.”

Dapagliflozin is known to effectively treat diabetes and also reduce the risk of these patients developing heart failure – a common complication of type 2 diabetes.

In this study, researchers wanted to find out whether the same medication could effectively treat patients already diagnosed with heart failure, whether they had the condition or not.

The trial looked at 4,744 patients from 20 countries around the world.

Researchers then measured the effectiveness of the drug against a placebo.

Around half of the patients enrolled in the trial did not have diabetes.

PA

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