A new combination of medication could treat a previously drug-resistant strain of gonorrhoea, according to scientists.

There has been increasing concern that resistance to treatment could become widespread, but now researchers have found that an antibiotic known as gentamicin can be effective when taken alongside another drug.

The latest treatment combines this antibiotic with azithromycin, which is usually prescribed in combination with a different drug called ceftriaxone.

Download the new Independent Premium app

Sharing the full story, not just the headlines

According to the results of a study which was published today in The Lancet medical journal, the new combination was found to be almost as effective in treating genital gonorrhoea, which is good news for doctors who are concerned that the existing treatment “is beginning to fail”.

In January, Public Health England revealed that two women had been infected with super-gonorrhoea, which was resistant to the first-choice treatment. Other cases have also been reported.

"Our current antibiotic treatment for gonorrhoea is beginning to fail and experience with previous drugs strongly suggests that this could become a widespread problem," said Professor Jonathan Ross, chief investigator from the University of Birmingham where the research was conducted.

The trial took place at 14 sexual health clinics in England between October 2014 and November  2016, and 720 patients were given either the current antibiotic treatment of ceftriaxone or the new combination.

A total of 98 per cent of those given the traditional combination were cured of gonorrhoea after two weeks, compared to 91 per cent of those treated with gentamicin.

While the trial found that gentamicin combined with azithromycin works almost as well as for genital gonorrhoea, it did not clear throat or rectal gonorrhoea as effectively, and researchers said further work is needed to find alternative treatments, with antibiotic resistance a growing problem.

Professor Hywel Williams, director of the NIHR's health technology assessment programme, said: "It's very worrying that cases of treatment-resistant gonorrhoea are now appearing across the globe.

"This research provides important new evidence that suggests that gentamicin with azithromycin could become a second-line treatment for patients who are resistant to ceftriaxone with this infectious disease.

Gonorrhoea is a sexually transmitted infection caused by bacteria called Neisseria gonorrhoeae, also called gonococcus, which is usually found in penis discharge and vaginal fluid. It does not usually lead to complications, but if left untreated can cause serious health issues including pelvic inflammatory disease among women.

Comments

Share your thoughts and debate the big issues

Learn more
Please be respectful when making a comment and adhere to our Community Guidelines.
  • You may not agree with our views, or other users’, but please respond to them respectfully
  • Swearing, personal abuse, racism, sexism, homophobia and other discriminatory or inciteful language is not acceptable
  • Do not impersonate other users or reveal private information about third parties
  • We reserve the right to delete inappropriate posts and ban offending users without notification

You can find our Community Guidelines in full here.

Create a commenting name to join the debate

Please try again, the name must be unique Only letters and numbers accepted
Loading comments...
Loading comments...
Please be respectful when making a comment and adhere to our Community Guidelines.
  • You may not agree with our views, or other users’, but please respond to them respectfully
  • Swearing, personal abuse, racism, sexism, homophobia and other discriminatory or inciteful language is not acceptable
  • Do not impersonate other users or reveal private information about third parties
  • We reserve the right to delete inappropriate posts and ban offending users without notification

You can find our Community Guidelines in full here.

Loading comments...
Loading comments...